PURPOSE Structural reversal of disc cupping is a known phenomenon after trabeculectomy. The aim of this retrospective, longitudinal, cross-sectional analysis was to evaluate the postoperative dynamics of Bruch's membrane opening-based morphometrics of the optic nerve head following glaucoma drainage device surgery. METHODS Forty-three eyes, treated by glaucoma drainage device surgery, were included in the study. Individual changes in the spectral domain optic coherence tomography (SD-OCT) parameters Bruch's membrane opening minimum rim width (BMO-MRW), Bruch's membrane opening minimum rim area (BMO-MRA) and peripapillary retinal nerve fiber layer (RNFL) thickness as well as mean defect in 30-2 perimetry were analyzed. Changes were correlated to postoperative intraocular pressure levels over time. Available follow-up visits were aggregated and grouped into a short-term follow-up (20 to 180 days after surgery), a midterm follow-up (181 to 360 days after surgery) and a long-term follow-up (more than 360 days after surgery). RESULTS In short-term follow-up, BMO-MRW and BMO-MRA increased significantly (p <= 0.034). This increase correlated negatively with the intraocular pressure at the time of the follow-up (Pearson's rho = - 0.49; p = 0.039). From 6 months after surgery on, there was no statistically significant change in BMO-MRW and BMO-MRA (p >= 0.207). RNFL thickness and mean defect of 30-2 perimetry showed no significant changes after GDD implantation (p >= 0.189). CONCLUSIONS Lowering of intraocular pressure by glaucoma drainage device surgery leads to an increase of Bruch's membrane opening based parameters in the first 6 months after surgery. These changes have to be taken into account when evaluating patients' longitudinal follow-up after glaucoma drainage device implantation.

中文翻译：

---

青光眼引流装置手术后基于布鲁赫膜开口的形态测量学的结构逆转动力学。

目的 椎间盘拔罐的结构逆转是小梁切除术后的一个已知现象。这项回顾性、纵向、横断面分析的目的是评估青光眼引流装置手术后基于布鲁赫膜开口的视神经乳头形态测量学的术后动态。方法 43 只眼，接受青光眼引流装置手术治疗，纳入研究。谱域光学相干断层扫描 (SD-OCT) 参数 Bruch 膜开口最小边缘宽度 (BMO-MRW)、Bruch 膜开口最小边缘区域 (BMO-MRA) 和视乳头周围视网膜神经纤维层 (RNFL) 厚度的个体变化分析了 30-2 视野中的平均缺陷。随着时间的推移，变化与术后眼压水平相关。可用的随访被汇总并分为短期随访（术后 20 至 180 天）、中期随访（术后 181 至 360 天）和长期随访（超过术后 360 天）。结果 在短期随访中，BMO-MRW 和 BMO-MRA 显着增加（p <= 0.034）。这种增加与随访时的眼内压呈负相关（Pearson's rho = - 0.49；p = 0.039）。从手术后 6 个月开始，BMO-MRW 和 BMO-MRA 没有统计学上的显着变化（p >= 0.207）。GDD 植入后 RNFL 厚度和 30-2 视野的平均缺陷显示没有显着变化（p > = 0.189）。结论青光眼引流装置手术降低眼压导致布鲁赫' s 手术后前 6 个月的基于膜开口的参数。在评估青光眼引流装置植入后患者的纵向随访时，必须考虑这些变化。