Fluorocarbons are novel systems in the fast-growing fields of diverse biomedical applications and fluorocarbon-water emulsions. However, characterization of these systems with modern measuring techniques such as drop profile analysis tensiometry is almost impossible because of practically identical refractive indexes and high-density differences. Due to the material properties of the fluorocarbon-water system, the invasive Du Noüy ring is the most appropriate method to measure interfacial tensions over long times. However, the influence of the ring on a fluorocarbon/water interface packed with phospholipids needs careful analysis. For the proof of methodology, the spinning drop tensiometry was used for comparison as a non-invasive technique to measure interfacial tension between water and perfluoroperhydrophenanthrene (PFPH) covered by 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) proving almost identical results. This demonstrates the validity of the invasive measurement technique for the studied system. The Du Noüy ring method was applied for further measurements of phospholipids with different chain lengths (1,2-dmyristoyl-sn-glycero-3-phostphatidylcholine, DMPC; 1,2-distearoyl-sn-glycero-3-phosphatidylcholine, DSPC) which revealed a difference in interfacial adsorption kinetics and equilibrium tensions. The Du Noüy ring tensiometry is appropriate to examine the slow adsorption kinetics of phospholipids emulsifying fluorocarbons. The results enable functional optimization of fluorocarbon emulsions regarding physical emulsification parameters and the selection of lipids.

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Du Noüy环和纺丝滴研究不同链长磷脂在碳氟化合物/水界面的吸附过程

碳氟化合物是各种生物医学应用和碳氟化合物-水乳液快速增长领域中的新型系统。然而，由于几乎相同的折射率和高密度差异，使用现代测量技术（例如液滴轮廓分析张力测定法）表征这些系统几乎是不可能的。由于碳氟化合物-水系统的材料特性，侵入性 Du Noüy 环是长期测量界面张力的最合适方法。然而，环对填充有磷脂的碳氟化合物/水界面的影响需要仔细分析。为了证明方法论，旋转滴张力测定法作为一种非侵入性技术被用于比较，以测量水和由 1 覆盖的全氟全氢菲 (PFP​​H) 之间的界面张力，2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) 证明几乎相同的结果。这证明了所研究系统的侵入式测量技术的有效性。Du Noüy 环法用于进一步测量不同链长的磷脂（1,2-dmyristoyl-sn-glycero-3-phostphatidylcholine, DMPC; 1,2-distearoyl-sn-glycero-3-phosphatidylcholine, DSPC）揭示了界面吸附动力学和平衡张力的差异。Du Noüy 环张力测定法适用于检查乳化碳氟化合物的磷脂的缓慢吸附动力学。结果使氟碳乳液在物理乳化参数和脂质选择方面的功能优化成为可能。这证明了所研究系统的侵入式测量技术的有效性。Du Noüy 环法用于进一步测量不同链长的磷脂（1,2-dmyristoyl-sn-glycero-3-phostphatidylcholine, DMPC; 1,2-distearoyl-sn-glycero-3-phosphatidylcholine, DSPC）揭示了界面吸附动力学和平衡张力的差异。Du Noüy 环张力测定法适用于检查乳化碳氟化合物的磷脂的缓慢吸附动力学。结果使氟碳乳液在物理乳化参数和脂质选择方面的功能优化成为可能。这证明了所研究系统的侵入式测量技术的有效性。Du Noüy 环法用于进一步测量不同链长的磷脂（1,2-dmyristoyl-sn-glycero-3-phostphatidylcholine, DMPC; 1,2-distearoyl-sn-glycero-3-phosphatidylcholine, DSPC）揭示了界面吸附动力学和平衡张力的差异。Du Noüy 环张力测定法适用于检查乳化碳氟化合物的磷脂的缓慢吸附动力学。结果使氟碳乳液在物理乳化参数和脂质选择方面的功能优化成为可能。2-dmyristoyl-sn-glycero-3-phostphatidylcholine, DMPC; 1,2-二硬脂酰-sn-甘油-3-磷脂酰胆碱，DSPC），它揭示了界面吸附动力学和平衡张力的差异。Du Noüy 环张力测定法适用于检查乳化碳氟化合物的磷脂的缓慢吸附动力学。结果使氟碳乳液在物理乳化参数和脂质选择方面的功能优化成为可能。2-dmyristoyl-sn-glycero-3-phostphatidylcholine, DMPC; 1,2-二硬脂酰-sn-甘油-3-磷脂酰胆碱，DSPC），它揭示了界面吸附动力学和平衡张力的差异。Du Noüy 环张力测定法适用于检查乳化碳氟化合物的磷脂的缓慢吸附动力学。结果使氟碳乳液在物理乳化参数和脂质选择方面的功能优化成为可能。