Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC occurrence based on incidence data (available through 2016) from population‐based cancer registries and mortality data (through 2017) from the National Center for Health Statistics. In 2020, approximately 147,950 individuals will be diagnosed with CRC and 53,200 will die from the disease, including 17,930 cases and 3,640 deaths in individuals aged younger than 50 years. The incidence rate during 2012 through 2016 ranged from 30 (per 100,000 persons) in Asian/Pacific Islanders to 45.7 in blacks and 89 in Alaska Natives. Rapid declines in incidence among screening‐aged individuals during the 2000s continued during 2011 through 2016 in those aged 65 years and older (by 3.3% annually) but reversed in those aged 50 to 64 years, among whom rates increased by 1% annually. Among individuals aged younger than 50 years, the incidence rate increased by approximately 2% annually for tumors in the proximal and distal colon, as well as the rectum, driven by trends in non‐Hispanic whites. CRC death rates during 2008 through 2017 declined by 3% annually in individuals aged 65 years and older and by 0.6% annually in individuals aged 50 to 64 years while increasing by 1.3% annually in those aged younger than 50 years. Mortality declines among individuals aged 50 years and older were steepest among blacks, who also had the only decreasing trend among those aged younger than 50 years, and excluded American Indians/Alaska Natives, among whom rates remained stable. Progress against CRC can be accelerated by increasing access to guideline‐recommended screening and high‐quality treatment, particularly among Alaska Natives, and elucidating causes for rising incidence in young and middle‐aged adults.

中文翻译：

---

2020 年结直肠癌统计数据

结直肠癌 (CRC) 是美国癌症死亡的第二大常见原因。每 3 年，美国癌症协会都会根据人群癌症登记处的发病率数据（截至 2016 年）和国家卫生统计中心的死亡率数据（截至 2017 年）提供 CRC 发生率的更新。到 2020 年，约有 147,950 人将被诊断出患有结直肠癌，53,200 人将死于该疾病，其中 50 岁以下的人将有 17,930 例病例和 3,640 例死亡。2012 年至 2016 年期间的发病率从亚洲/太平洋岛民的 30 例（每 10 万人）到黑人的 45.7 例和阿拉斯加原住民的 89 例不等。2000 年代筛查年龄人群的发病率在 2011 年至 2016 年期间持续快速下降，65 岁及以上人群（截至 3. 3%），但在 50 至 64 岁的人群中出现逆转，其中每年增加 1%。在年龄小于 50 岁的个体中，近端和远端结肠以及直肠肿瘤的发病率每年增加约 2%，这是由非西班牙裔白人趋势驱动的。2008 年至 2017 年期间，65 岁及以上人群的 CRC 死亡率每年下降 3%，50 至 64 岁人群每年下降 0.6%，而 50 岁以下人群每年增长 1.3%。50 岁及以上人群的死亡率下降幅度最大的是黑人，他们也是 50 岁以下人群中唯一下降的趋势，不包括美洲印第安人/阿拉斯加原住民，他们的死亡率保持稳定。