Additives which are used in food contact materials (FCMs) such as plasticizers, antioxidants and photoinitiators (PIs) are potential hazards to humans and the environment. In this research, a simple, rapid, green and sensitive supercritical fluid chromatography (SFC) method combined with ultrasonic-assisted solvent extraction was proposed for the simultaneous analysis of di-(2-ethylhexyl) phthalate (DEHP) and five photoinitiators. In order to achieve the best experimental effect, both the ultrasonic extraction conditions and the SFC parameters were investigated. Under the optimized conditions, six additives were completely separated in 7 min. Meanwhile, a good linearity (R² > 0.999) was obtained in the wide range of 0.10–20 μg mL⁻¹ (except DEHP was 0.5–100 μg mL⁻¹). The limits of detection (LODs) and limits of quantification (LOQs) ranged from 0.021–0.150 μg mL⁻¹ and 0.070–0.500 μg mL⁻¹, respectively. Also, the recovery results (91.2–108.3%) and precision values (RSDs < 8.1%, n = 6) were satisfying. The proposed method was applied for the measurement of additives in real samples, which provided a novel alternative for monitoring the quality and safety of FCMs.

中文翻译：

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超声辅助萃取-超临界流体色谱法同时测定食品接触材料中邻苯二甲酸二（2-乙基己基）酯和5种光引发剂

食品接触材料（FCM）中使用的添加剂，例如增塑剂，抗氧化剂和光引发剂（PI），对人体和环境均具有潜在危害。在这项研究中，提出了一种简单，快速，绿色和灵敏的超临界流体色谱法（SFC）与超声辅助溶剂萃取相结合的方法，用于同时分析邻苯二甲酸二（2-乙基己基）酯（DEHP）和五种光引发剂。为了获得最佳的实验效果，研究了超声提取条件和SFC参数。在优化条件下，六种添加剂在7分钟内被完全分离。同时，在0.10–20μgmL ^-1的宽范围内获得了良好的线性（R ² > 0.999）（除DEHP为0.5–100μgmL ^-1）。检测限（LOD）和定量限（LOQ）分别为0.021-0.150μgmL ^-1和0.070-0.500μgmL ^-1。而且，回收率结果（91.2–108.3％）和精度值（RSDs <8.1％，n = 6）令人满意。该方法用于实际样品中添加剂的测定，为监测FCM的质量和安全性提供了一种新的选择。