A bulky carboxylic acid bearing one 1-adamantylmethyl and two methyl substituents at the α-position is demonstrated to work as an efficient carboxylate ligand source in Pd-catalyzed intermolecular C(sp²)–H bond arylation reactions. The reactions proceeded smoothly under mild conditions, taking advantage of the steric bulk of the carboxylate ligands.

中文翻译：

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Pd催化的分子间C–H键芳基化反应：羧酸盐配体体积的影响

在α-位带有一个1-金刚烷基甲基和两个甲基取代基的大体积羧酸被证明在Pd催化的分子间C（sp ²）-H键芳基化反应中可作为有效的羧酸盐配体来源。利用羧酸配体的空间体积，反应在温和的条件下顺利进行。