Temperature-responsive macro-porous cryogels of poly(N-iospropylacryamide-co-acrylamido-2-methylpropane sulfonic acid) [P(NIPAM-co-AMPS)] were prepared through redox-initiated cryo-polymerization at −12, −18 and −24 °C. Silver or gold nanoparticles (AgNPs or AuNPs) were formed inside P(NIPAM-co-AMPS) cryogels through the thermal reduction of absorbed AgNO₃ or HAuCl₄, resulting in hybrid cryogels immobilized with AgNPs or AuNPs. Fourier transform infrared spectroscopy, thermal gravimetric analysis and X-ray diffraction confirmed the chemical composition. Cryogel morphology and nanoparticle distribution were investigated through scanning and transmission electron microscopies. By checking swelling ratio in neutral water, the temperature response of cryogels was identified. The hybrid cryogels were used as the catalysts to reduce p-nitrophenol with NaBH₄ at different temperatures and pHs. The hybrid cryogel with AuNPs had the higher catalytic activity than the counterpart hybrid cryogel with AgNPs. The catalytic activity of hybrid cryogels increased with temperature and pH. The temperature response of cryogels facilitated their isolation from the reaction mixture. Since AuNPs were fixed tightly onto the cryogel pore-wall and hardly lost, hybrid cryogels with AuNPs demonstrated no decrease in catalytic activity for 5 cycles of p-nitrophenol reduction.

聚的温度响应宏观多孔冷冻凝胶（Ñ -iospropylacryamide-共-acrylamido基-2-甲基丙磺酸）[P（NIPAM-共-AMPS）]通过氧化还原引发的低温聚合在-12制备，-18和−24°C。通过热还原吸收的AgNO ₃或HAuCl _4，在P（NIPAM- co -AMPS）低温凝胶内部形成了银或金纳米颗粒（AgNP或AuNP），导致混合Agogs或AuNPs固定的冷冻凝胶。傅里叶变换红外光谱，热重分析和X射线衍射证实了化学成分。通过扫描和透射电子显微镜研究了冷冻凝胶的形态和纳米颗粒的分布。通过检查中性水中的溶胀率，可以确定冰晶的温度响应。杂化低温凝胶用作催化剂，以NaBH ₄还原对硝基苯酚在不同的温度和pH值。具有AuNPs的混合冷冻凝胶比具有AgNPs的对应混合冷冻凝胶具有更高的催化活性。杂化低温凝胶的催化活性随温度和pH值的增加而增加。冰晶石的温度响应促进了它们从反应混合物中的分离。由于AuNPs牢固地固定在冷冻凝胶孔壁上且几乎不丢失，因此具有AuNPs的混合冷冻凝胶显示5个对硝基苯酚还原反应的催化活性没有降低。