The solid–liquid equilibrium solubility of isatoic anhydride in 12 pure solvents (methanol, ethanol, 1-propanol, isopropyl alcohol, methyl acetate, ethyl acetate, propyl acetate, isopropyl acetate, acetone, 2-butanone, acetonitrile, and 1,4-dioxane) at T = 288.15 to 328.15 K was measured by the gravimetric method under atmospheric pressure. Experimental results demonstrate that the mole fraction solubility of isatoic anhydride in these selected solvents increased with the increase of temperature, and the dissolution behavior is affected by multiple factors like polarity, H-bond interaction, cohesive energy density, etc. The modified Apelblat model, the van’t Hoff model, the nonrandom two-liquid model, and the λh model were used to correlate the experimental solubility data. The maximum values of the relative average deviation and root-mean-square deviation were no more than 4.23 × 10^–2 and 5.31 × 10^–4, respectively. Furthermore, the thermodynamic properties including the mixing Gibbs energy, mixing enthalpy, and mixing entropy were calculated, which indicates that the dissolution of isatoic anhydride was a spontaneous and entropy-favorable process.

中文翻译：

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288.15至328.15 K温度下12种纯溶剂中异丙基酸酐的溶解度测量和数据关联

异丙酸酐在12种纯溶剂（甲醇，乙醇，1-丙醇，异丙醇，乙酸甲酯，乙酸乙酯，乙酸丙酯，乙酸异丙酯，丙酮，2-丁酮，乙腈和1,4-的固-液平衡溶解度）中通过重量分析法在大气压下测量T＝ 288.15至328.15K时的二恶烷。实验结果表明，等温酸酐在这些选定溶剂中的摩尔分数溶解度随温度的升高而增加，并且其溶解行为受极性，氢键相互作用，内聚能密度等多种因素的影响。改良的Apelblat模型该范特霍夫模型中，非随机双液体模型，和λ ħ模型用于关联实验溶解度数据。相对平均偏差和均方根偏差的最大值分别不超过4.23×10 ^–2和5.31×10 ^–4。此外，计算了包括混合吉布斯能量，混合焓和混合熵在内的热力学性质，这表明等酸酐的溶解是自发的且有利于熵的过程。