Neural tube defects (NTD)s are common birth defects with a multifactorial etiology. Findings from human studies examining environmental (non‐inherited) exposures tend to be inconclusive. In particular, although animal studies of alcohol exposure and NTDs support its teratogenic potential, human studies are equivocal. Using data from the National Birth Defects Prevention Study (NBDPS), associations between maternal periconceptional (1 month before through 1 month after conception) alcohol consumption and NTDs in offspring were examined.

中文翻译：

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孕期饮酒与神经管缺陷之间的关联：国家出生缺陷预防研究的结果，1997-2011。

神经管缺陷 (NTD) 是具有多因素病因的常见出生缺陷。检查环境（非遗传）暴露的人类研究结果往往没有定论。特别是，虽然酒精暴露和 NTD 的动物研究支持其致畸潜力，但人体研究却模棱两可。使用来自国家出生缺陷预防研究 (NBDPS) 的数据，检查了母亲围孕期（受孕前 1 个月至受孕后 1 个月）饮酒与后代 NTD 之间的关联。