当前位置: X-MOL 学术Expert Rev. Mol. Diagn. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Salivary protein biomarkers for head and neck cancer.
Expert Review of Molecular Diagnostics ( IF 5.1 ) Pub Date : 2020-01-27 , DOI: 10.1080/14737159.2020.1722102
José M Amenábar 1, 2 , Bruna Machado Da Silva 1 , Chamindie Punyadeera 2
Affiliation  

Introduction: Saliva has gained attention as an important diagnostic fluid because it contains biomolecules that have the potential to detect early-stage cancer or to monitor the response to treatment in patients. Several saliva-based proteins have been proposed as potential biomarkers for head and neck cancers (HNC).Areas covered: This review aims to provide an update on saliva-based protein biomarkers for HNC, often studied in observational research and clinical trials.Expert opinion: Despite the increasing number of studies relating to salivary proteins as biomarkers for HNC, there is no consensus regarding which proteins have the best clinical utility. Most studies have analyzed individual proteins and not a protein panel approach. It must be considered that combining different proteins as a panel can increase the accuracy and will have the potential to change the current clinical practice for HNC patients.

中文翻译:

唾液蛋白质生物标志物,用于头颈癌。

简介:唾液作为一种重要的诊断液已受到关注,因为它含有生物分子,可以检测早期癌症或监测患者对治疗的反应。有人提出了几种基于唾液的蛋白质作为头颈癌(HNC)的潜在生物标志物涵盖的领域:本综述旨在提供有关HNC的基于唾液的蛋白质生物标志物的最新信息,专家经常在观察性研究和临床试验中对其进行研究。 :尽管有关唾液蛋白作为HNC生物标志物的研究越来越多,但关于哪种蛋白具有最佳临床效用尚无共识。大多数研究都分析了单个蛋白质,而不是蛋白质组方法。
更新日期:2020-01-27
down
wechat
bug