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Neuronal GDPGP1 and glycogen metabolism: friend or foe?
The Journal of Cell Biology Pub Date : 2020-01-23 , DOI: 10.1083/jcb.202001006 Neel S Singhal 1, 2 , Evan M Lee 2 , Dengke K Ma 2, 3
The Journal of Cell Biology Pub Date : 2020-01-23 , DOI: 10.1083/jcb.202001006 Neel S Singhal 1, 2 , Evan M Lee 2 , Dengke K Ma 2, 3
Affiliation
The adult brain consumes glucose for energy needs and stores glucose as glycogen mainly in astrocytes. Schulz et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201807127) identify the stress-regulated metabolic enzyme GDPGP1 that promotes neuronal survival likely through glycogen reserves in mouse and C. elegans neurons.
中文翻译:
神经元 GDPGP1 和糖原代谢:朋友还是敌人?
成人大脑消耗葡萄糖以满足能量需求,并将葡萄糖作为糖原主要储存在星形胶质细胞中。舒尔茨等人。(2020. J. Cell Biol.https://doi.org/10.1083/jcb.201807127) 鉴定出应激调节代谢酶 GDPGP1,该酶可能通过小鼠和秀丽隐杆线虫神经元中的糖原储备来促进神经元存活。
更新日期:2020-01-23
中文翻译:
神经元 GDPGP1 和糖原代谢:朋友还是敌人?
成人大脑消耗葡萄糖以满足能量需求,并将葡萄糖作为糖原主要储存在星形胶质细胞中。舒尔茨等人。(2020. J. Cell Biol.https://doi.org/10.1083/jcb.201807127) 鉴定出应激调节代谢酶 GDPGP1,该酶可能通过小鼠和秀丽隐杆线虫神经元中的糖原储备来促进神经元存活。