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Mild behavioral impairment is associated with β-amyloid but not tau or neurodegeneration in cognitively intact elderly individuals
Alzheimer's & Dementia ( IF 14.0 ) Pub Date : 2020-01-01 , DOI: 10.1002/alz.12007
Firoza Z Lussier 1, 2 , Tharick A Pascoal 1, 2 , Mira Chamoun 1, 2 , Joseph Therriault 1, 2 , Cécile Tissot 1, 2 , Mélissa Savard 1 , Min Su Kang 1, 2, 3 , Sulantha Mathotaarachchi 1 , Andrea L Benedet 1, 2 , Marlee Parsons 1, 2 , Muhammad Naveed Iqbal Qureshi 1, 2 , Émilie M Thomas 1, 2 , Monica Shin 1, 2 , Laurie-Anne Dion 1 , Gassan Massarweh 3, 4 , Jean-Paul Soucy 3, 4 , I-Huang Tsai 3 , Paolo Vitali 5 , Zahinoor Ismail 6, 7 , Pedro Rosa-Neto 1, 2, 3 , Serge Gauthier 5
Affiliation  

Mild behavioral impairment (MBI) is characterized by the emergence of neuropsychiatric symptoms in elderly persons. Here, we examine the associations between MBI and Alzheimer's disease (AD) biomarkers in asymptomatic elderly individuals.

中文翻译:

在认知完整的老年人中,轻度行为障碍与 β-淀粉样蛋白有关,但与 tau 蛋白或神经变性无关

轻度行为障碍 (MBI) 的特征是老年人出现神经精神症状。在这里,我们研究了无症状老年人中 MBI 与阿尔茨海默病 (AD) 生物标志物之间的关联。
更新日期:2020-01-01
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