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Tracking disease progression in familial and sporadic frontotemporal lobar degeneration: Recent findings from ARTFL and LEFFTDS
Alzheimer's & Dementia ( IF 14.0 ) Pub Date : 2020-01-01 , DOI: 10.1002/alz.12004
Howard J Rosen 1 , Bradley F Boeve 2 , Adam L Boxer 1
Affiliation  

Familial frontotemporal lobar degeneration (f‐FTLD) due to autosomal dominant mutations is an important entity for developing treatments for FTLD. The Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) and Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) longitudinal studies were designed to describe the natural history of f‐FTLD.

中文翻译:

追踪家族性和散发性额颞叶变性的疾病进展:ARTFL 和 LEFFTDS 的最新发现

由于常染色体显性突变导致的家族性额颞叶变性 (f-FTLD) 是开发 FTLD 治疗方法的重要实体。额颞叶变性 (ARTFL) 的推进研究和治疗和家族性额颞叶痴呆患者的纵向评估 (LEFFTDS) 纵向研究旨在描述 f-FTLD 的自然史。
更新日期:2020-01-01
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