Antimicrobials have been commonly used to control bacterial diseases in farm animals. The efficacy of these drugs deterred the development of other control measures, such as vaccines, which are currently getting more attention due to the increased concern about antimicrobial resistance. Glässer's disease is caused by Glaesserella (Haemophilus) parasuis and affects pork production around the world. Balance between colonization and immunity seems to be essential in disease control. Reduction in antimicrobial use in veterinary medicine requires the implementation of preventive measures, based on alternative tools such as vaccination and other strategies to guarantee a beneficial microbial colonization of the animals. The present review summarizes and discusses the current knowledge on diagnosis and control of Glässer's disease, including prospects on alternatives to antimicrobials.

中文翻译：

---

格拉瑟氏病最新动态：如何在限制性使用抗生素的情况下控制疾病。

抗菌剂已普遍用于控制农场动物的细菌性疾病。这些药物的功效阻碍了其他控制措施的发展，例如疫苗，由于对抗菌素耐药性的关注日益增加，目前正受到越来越多的关注。格拉塞尔氏病是由副猪嗜血杆菌引起的，并影响世界各地的猪肉生产。在疾病控制中，定植和免疫之间的平衡似乎至关重要。减少兽药抗菌剂的使用需要采取预防措施，这些措施要基于疫苗和其他策略等替代工具，以确保动物对微生物的有益菌落定植。本综述总结并讨论了有关格拉塞尔病诊断和控制的最新知识，