Pseudomonas aeruginosa biofilm formation is a primary cause of chronic infections. This has been a highly active area of research over the past two decades due to causing high mortality risks in immunocompromised patients. This study evaluates global trends in the dynamic and rapidly evolving field of P. aeruginosa biofilm research through bibliometric and visualized analyses. Publications from 1994 to 2018 on P. aeruginosa biofilm research were retrieved from Web of Science, Scopus, and PubMed, and their bibliometric data were systematically studied. The VOSviewer software was used to conduct global analyses of bibliographic coupling, coauthorship, cocitation, and co‐occurrence. A total of 9,527 publications were included in this study. The overall number of publications and research interest in the field displayed a strongly rising trend. The USA made the greatest contributions to the field, with the highest h‐index and number of citations compared with other countries, while Denmark had the highest average citation per publication. The Journal of Bacteriology had the highest number of publications in the field, while the University of Copenhagen was the institution with the highest contribution influence. Co‐occurrence network maps revealed that the most prominent topics in P. aeruginosa biofilm research were mechanistic studies, in vitro/in vivo studies, and biofilm formation studies. Pseudomonas aeruginosa biofilms constitute a dynamic research area in microbiology with increasing global research interest. Future studies will likely focus on investigating the mechanisms of biofilm formation to solve infection‐associated clinical problems.

中文翻译：

---

过去二十年来铜绿假单胞菌生物膜研究的全球趋势：文献计量研究。

铜绿假单胞菌生物膜的形成是慢性感染的主要原因。在过去的二十年中，由于在免疫功能低下的患者中引起很高的死亡风险，这一直是一个非常活跃的研究领域。这项研究通过文献计量学和可视化分析评估了铜绿假单胞菌生物膜研究动态和快速发展领域的全球趋势。1994年至2018年关于铜绿假单胞菌的出版物从Web of Science，Scopus和PubMed检索了生物膜研究，并对它们的文献计量数据进行了系统地研究。使用VOSviewer软件对书目耦合，共同作者，引用和共现进行全局分析。本研究共纳入9,527种出版物。该领域的出版物总数和研究兴趣呈现出强劲的增长趋势。美国在该领域的贡献最大，与其他国家/地区相比，h指数和被引次数最高，而丹麦的平均被引次数最高。在细菌学杂志该领域的出版物数量最多，而哥本哈根大学则是影响力最大的机构。共现网络图显示，铜绿假单胞菌生物膜研究中最突出的主题是机械研究，体外/体内研究和生物膜形成研究。铜绿假单胞菌生物膜构成了微生物学中一个动态的研究领域，具有越来越高的全球研究兴趣。未来的研究可能会集中于研究生物膜形成的机制来解决与感染相关的临床问题。