AIM We investigated the association between acculturation strategies and cardiometabolic risk among South Asian (SA) immigrants in the US. METHODS In this cross-sectional analysis of data from 849 SA participants in the Mediators of Atherosclerosis in SAs Living in America (MASALA), we performed multidimensional measures of acculturation to categorize the participants into three acculturation classes: separation (preference for SA culture), assimilation (preference for US culture), and integration (similar preference for both cultures). Differences in glycemic indices, blood pressure, lipid parameters and body composition by acculturation strategy were examined. RESULTS Women in the integration class had the lowest prevalence of diabetes (16.4%), prediabetes (29.7%), fasting and 2-h glucose compared to women in the separation class with the highest prevalence of diabetes (29.3%), prediabetes (31.5%), fasting and 2-h glucose and 2-hr insulin (all p < 0.05). Women in the assimilation class had significantly lower triglycerides, BMI, and waist circumference and higher HDL compared to women in the separation class after adjusting for age, study site, and years in the US. After additionally accounting for socioeconomic/lifestyle factors, women in the assimilation class had significantly lower triglyceride and higher HDL levels compared to women in the separation class (p < 0.01). There was no significant association between acculturation strategies and cardiometabolic risk in SA men. CONCLUSION SA women who employed an assimilation or integration strategy had a more favorable cardiometabolic profile compared to women using a separation strategy. Future research should investigate the behavioral and psychosocial pathways linking acculturation strategies with cardiometabolic health to inform preventive interventions among SAs living in America.

中文翻译：

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美国南亚人的文化适应与心血管疾病危险因素的关系：MASALA研究的发现。

目的我们调查了美国南亚（SA）移民的适应策略与心脏代谢风险之间的关联。方法在对来自美国SAs动脉粥样硬化介导者（MASALA）的849名SA参与者的数据进行的横断面分析中，我们进行了多维的容忍度测量，将参与者分为三类容忍类别：分离（偏好SA文化），同化（偏爱美国文化）和融合（偏爱两种文化）。通过适应策略检查了血糖指数，血压，脂质参数和身体成分的差异。结果融合型女性的糖尿病患病率最低（16.4％），糖尿病前患病率（29.7％），空腹和2小时葡萄糖与糖尿病最高患病率（29.3％），糖尿病前期（31.5％），空腹和2小时葡萄糖和2小时胰岛素的女性相比（均p <0.05）。在调整了年龄，研究地点和年限之后，与分离班女性相比，同化班女性的甘油三酸酯，BMI和腰围明显降低，HDL较高。在进一步考虑了社会经济/生活方式因素之后，与隔离类中的女性相比，同化类中的女性甘油三酯水平明显降低，HDL水平较高（p <0.01）。SA男性的适应策略与心脏代谢风险之间无显着相关性。结论与采用分离策略的女性相比，采用同化或融合策略的SA妇女的心脏代谢特征更佳。未来的研究应调查将适应策略与心脏代谢健康联系起来的行为和社会心理途径，以为居住在美国的SA中的预防性干预提供信息。