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The Guangzhou Twin Eye Study: 2019 Update
Twin Research and Human Genetics ( IF 0.9 ) Pub Date : 2020-02-04 , DOI: 10.1017/thg.2019.118
Xiaohu Ding 1 , Wei Wang 1 , Jane Scheetz 2 , Mingguang He 1, 2, 3
Affiliation  

The primary aim of the Guangzhou Twin Eye Study (GTES) is to explore the impact that genes and environmental influences have on common eye diseases. Since 2006, approximately 1300 pairs of twins, aged 7–15 years, were enrolled at baseline. Progressive phenotypes, such as cycloplegic refraction, axial length, height and weight, have been collected annually. Nonprogressive phenotypes such as parental refraction, corneal thickness, fundus photo, intraocular pressure and DNA were collected once at baseline. We are collaborating with fellow international twin researchers and psychologists to further explore links with general medical conditions. In this article, we review the history, major findings and future research directions for the GTES.

中文翻译:

广州双眼研究:2019 年更新

广州双眼研究(GTES)的主要目的是探索基因和环境影响对常见眼病的影响。自 2006 年以来,大约 1300 对年龄在 7-15 岁的双胞胎在基线时被纳入研究。每年都会收集渐进性表型,例如睫状肌麻痹屈光度、眼轴长度、身高和体重。在基线时收集一次非进行性表型,例如父母屈光度、角膜厚度、眼底照片、眼压和 DNA。我们正在与国际双胞胎研究人员和心理学家合作,进一步探索与一般医疗状况的联系。在本文中,我们回顾了 GTES 的历史、主要发现和未来的研究方向。
更新日期:2020-02-04
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