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Stimulus Onset Hub: an Open-Source, Low Latency, and Opto-Isolated Trigger Box for Neuroscientific Research Replicability and Beyond.
Frontiers in Neuroinformatics ( IF 3.5 ) Pub Date : 2020-02-06 , DOI: 10.3389/fninf.2020.00002
Charles E Davis 1 , Jacob G Martin 1 , Simon J Thorpe 1
Affiliation  

Accurate stimulus onset timing is critical to almost all behavioral research. Auditory, visual, or manual response time stimulus onsets are typically sent through wires to various machines that record data such as: eye gaze positions, electroencephalography, stereo electroencephalography, and electrocorticography. These stimulus onsets are collated and analyzed according to experimental condition. If there is variability in the temporal accuracy of the delivery of these onsets to external systems, the quality of the resulting data and scientific analyses will degrade. Here, we describe an approximately 200 dollar Arduino based system and associated open-source codebase that achieved a maximum of 4 microseconds of delay from the inputs to the outputs while electrically opto-isolating the connected external systems. Using an oscilloscope, the device is configurable for the different environmental conditions particular to each laboratory (e.g., light sensor type, screen type, speaker type, stimulus type, temperature, etc). This low-cost open-source project delivered electrically isolated digital stimulus onset Transistor-Transistor Logic triggers with an input/output delay of 4 μs, and was successfully tested with seven different external systems that record eye and neurological data.

中文翻译:

Stimulus Onset Hub:用于神经科学研究可复制性及其他方面的开源、低延迟和光隔离触发盒。

准确的刺激开始时间对几乎所有的行为研究都至关重要。听觉、视觉或手动响应时间刺激开始通常通过电线发送到各种记录数据的机器,例如:眼睛注视位置、脑电图、立体脑电图和皮层电图。根据实验条件对这些刺激开始进行整理和分析。如果向外部系统提供这些发作的时间准确性存在差异,则所得数据和科学分析的质量将会下降。在这里,我们描述了一个大约 200 美元的基于 Arduino 的系统和相关的开源代码库,它实现了从输入到输出的最大 4 微秒延迟,同时对连接的外部系统进行了光电隔离。使用示波器,该设备可针对每个实验室特有的不同环境条件进行配置(例如,光传感器类型、屏幕类型、扬声器类型、刺激类型、温度等)。这个低成本的开源项目提供了输入/输出延迟为 4 μs 的电隔离数字刺激起始晶体管-晶体管逻辑触发器,并成功地通过七种记录眼睛和神经数据的外部系统进行了测试。
更新日期:2020-02-06
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