Heliolactone is one of the earliest identified non-canonical strigolactones. Its concise synthesis was achieved by employing Knoevenagel-type condensation and semi-reduction of a malonate intermediate as the key steps. This synthesis was performed in a non-stereoselective manner, and thus a racemic and diastereomeric mixture of heliolactone was obtained. The developed synthetic route is fairly concise and straightforward.

中文翻译：

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简洁地合成了葵花内酯，这是一种从向日葵中分离出来的非规范性内酯。

Heliolactone是最早发现的非规范性strigolactones之一。通过使用Knoevenagel型缩合和丙二酸酯中间体的半还原作为关键步骤，可以实现其简洁的合成。该合成以非立体选择性的方式进行，因此获得了内酯的消旋体和非对映体混合物。发达的合成路线相当简洁明了。