The emergence of antimicrobial resistance in human and veterinary bacterial pathogens has led to concerns regarding the use of antimicrobials in veterinary medicine. Consequently, regulatory agencies have developed procedures for assessing the risk associated with the use of a specific antimicrobial as part of the drug approval process. Due consideration for the importance (priority categorization) of the antimicrobial to human medicine is part of this risk assessment process. Additionally, nongovernmental organizations have developed antimicrobial categorization schemes to protect the use and effectiveness of these medicines. However, the goals and methods of the various categorization schemes vary, resulting in final categorizations that are different. Although harmonizing these schemes would bring clarity to antimicrobial resistance discussions and policy, it has the disadvantage of not accounting for regional antimicrobial resistance and use, potentially removing effective medicines from clinical use in situations where they are wholly appropriate. Antimicrobials should be classified in a One Health manner, where both physician and veterinarian share the responsibility for antimicrobial use. The purpose of this article is to summarize current antimicrobial categorization schemes using illustrative examples to highlight differences and provide perspectives on the impact of the current schemes and future directions.

中文翻译：

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兽医用抗菌药物分类的当前和未来展望

人类和兽医细菌病原体中抗菌素耐药性的出现引起了人们对兽药中使用抗菌素的担忧。因此，监管机构制定了评估与使用特定抗微生物药物相关的风险的程序，作为药物批准过程的一部分。适当考虑抗菌素对人类医学的重要性（优先级分类）是此风险评估过程的一部分。此外，非政府组织制定了抗菌药物分类计划，以保护这些药物的使用和有效性。但是，各种分类方案的目标和方法各不相同，导致最终的分类也不同。虽然协调这些计划将使抗微生物药物耐药性讨论和政策变得清晰，但它的缺点是没有考虑区域抗微生物药物耐药性和使用情况，可能会在完全合适的情况下将有效药物从临床使用中移除。抗菌药物应以一种健康的方式分类，医生和兽医共同负责抗菌药物的使用。本文的目的是使用说明性示例总结当前的抗菌分类方案，以突出差异并提供有关当前方案和未来方向影响的观点。在完全合适的情况下，可能会从临床使用中去除有效药物。抗菌药物应以一种健康的方式分类，医生和兽医共同负责抗菌药物的使用。本文的目的是使用说明性示例总结当前的抗菌分类方案，以突出差异并提供有关当前方案和未来方向影响的观点。在完全合适的情况下，可能会从临床使用中去除有效药物。抗菌药物应以一种健康的方式分类，医生和兽医共同负责抗菌药物的使用。本文的目的是使用说明性示例总结当前的抗菌分类方案，以突出差异并提供有关当前方案和未来方向影响的观点。