Background

Patients with fibromyalgia syndrome (FMS) usually display a decrease in health-related quality of life (HRQoL). This decrease in HRQoL is related to clinical pain, anxiety, and depression. This cross-sectional study analyzes the mediating role of pain-coping strategies (especially catastrophizing) in the negative relationships of pain, anxiety, depression, and HRQoL in FMS.

Methods

One hundred and thirteen women with FMS and 63 healthy women were assessed using the Short-Form Health Survey (SF-36). Participants completed self-report questionnaires to evaluate clinical pain, anxiety, depression, and pain-coping strategies.

Results

Pain catastrophizing was inversely associated with the physical function, general health perception, vitality, emotional role, mental health, the physical and mental general components, and the global index of HRQoL, with percentages of variance explained ranging between 9 and 18%. Cognitive distraction showed a positive association with the physical function, general health perception, vitality, emotional role, mental health, physical component, and global index of HRQoL, with percentages of variance explained ranging between 4 and 7%. Mediation analysis showed that catastrophizing mediates the negative influence of clinical pain and trait-anxiety on the physical function, general health perception, vitality, mental health, and global index of HRQoL. No mediating effect of pain catastrophizing on the relation between depression and HRQoL was observed.

Conclusions

Patients with FMS exhibited markedly lower HRQoL than healthy individuals. While pain catastrophizing was inversely related to several domains of HRQL, associations were positive for cognitive distraction. Catastrophizing mediates the negative influence of clinical pain and trait-anxiety on HRQoL. Therefore, cognitive behavioral treatments focused on adaptive management and control of catastrophizing and negative emotional states may be helpful.

中文翻译：

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痛苦的灾难性传播介导了疼痛和特质焦虑对纤维肌痛健康相关生活质量的负面影响。

背景

纤维肌痛综合征（FMS）患者通常表现出与健康相关的生活质量（HRQoL）下降。HRQoL的下降与临床疼痛，焦虑和抑郁有关。这项横断面研究分析了FMS中疼痛应对策略（尤其是灾难性疾病）在疼痛，焦虑，抑郁和HRQoL的负面关系中的中介作用。

方法

使用“简短形式健康调查”（SF-36）对113名FMS妇女和63名健康妇女进行了评估。参与者完成了自我报告调查问卷，以评估临床疼痛，焦虑，抑郁和疼痛应对策略。

结果

疼痛灾难性疾病与身体机能，总体健康感知，活力，情绪作用，心理健康，身心一般组成部分以及HRQoL的整体指数呈负相关，被解释的差异百分比在9％至18％之间。认知分心显示出与HRQoL的身体机能，总体健康感知，活力，情绪作用，心理健康，身体成分和整体指数呈正相关，所解释的差异百分比在4％至7％之间。调解分析表明，灾难性化解对临床疼痛和特质焦虑对身体机能，总体健康知觉，活力，精神健康和HRQoL的总体指数的负面影响。

结论

FMS患者的HRQoL明显低于健康个体。虽然疼痛灾难性与HRQL的多个领域成反比，但关联对认知分心是积极的。灾难性化解了临床疼痛和特质焦虑对HRQoL的负面影响。因此，专注于适应性管理和控制灾难性和负面情绪状态的认知行为治疗可能会有所帮助。