Although alcohol-associated liver disease has long been a major component of the liver disease landscape, it was overshadowed by chronic hepatitis C until recently. Nevertheless, with the declining incidence of hepatitis C in the wake of highly effective antiviral therapy, attention has shifted to the increasing burden of alcohol-associated liver disease. The incidence of advanced alcohol-associated liver disease, including acute alcoholic hepatitis and alcohol-associated cirrhosis, is rising in parallel with increasing rates of alcohol use disorders. As a result, alcohol-associated liver disease is now one of the most common indications for liver transplantation. Rates of liver transplantation for acute alcoholic hepatitis are rising as well in spite of the sparse guidance regarding candidate selection, counseling, postoperative care, long-term follow-up, and other best practices. To this day, liver transplant for acute alcoholic hepatitis remains a hotly debated clinical controversy.

中文翻译：

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严重酒精性肝炎的早期肝移植。

尽管与酒精有关的肝病长期以来一直是肝病领域的主要组成部分，但直到最近，它仍被慢性丙型肝炎所掩盖。然而，随着高效抗病毒治疗后丙型肝炎发病率的下降，人们的注意力已转移到与酒精相关的肝病日益增加的负担上。晚期酒精相关性肝病（包括急性酒精性肝炎和酒精相关性肝硬化）的发生率与酒精使用障碍率的上升同时上升。结果，酒精相关的肝病现已成为肝移植的最常见适应症之一。尽管在候选人选择，咨询，术后护理，指导，治疗等方面的指导很少，但急性酒精性肝炎的肝移植率也在上升。长期跟进和其他最佳做法。时至今日，急性酒精性肝炎的肝移植仍是一个备受争议的临床争议。