Deaths of native scavenging pigs were reported in mid‐November 2015 at Nageswari sub‐district, Kurigram district of Bangladesh. The investigation for a suspected classical swine fever (CSF) outbreak was accomplished via a joint outbreak investigation team from Department of Livestock Services (DLS) and Food and Agriculture Organization, Emergency Center for Transboundary Animal Disease (FAO‐ECTAD), Bangladesh. Out of 592 pigs, 396 were infected and among them 263 died. The attack rate and case fatality rate were 66.9% and 66.4%, respectively. The epidemic curve constructed using the data captured from the CSF outbreak site was nearly bell‐shaped, indicating a point source epidemic. The basic reproduction numbers (R0) were estimated to be 1.6 (95% Confidence interval [CI]: 1.5–1.7) and 1.5 (95% CI: 1.3–1.7) based on attack rate and exponential growth rate methods, respectively. Adult pigs showed signs of high fever, staggering gait and depression, whereas piglets either died without any premonitory signs or purulent exudates in the eyes were observed. Post‐mortem examination was carried out on a 6‐month‐old piglet. The necropsy findings included were swollen lymph nodes deep red in colour, and haemorrhages on serous and mucous membranes of the intestinal organs together with button‐like ulceration in the intestines. Nasal swabs and tissue samples (spleen, lung and liver) were tested using real‐time reverse transcriptase polymerase chain reaction (RT‐qPCR) and found to be positive for CSF virus. One‐step RT‐PCR was used to amplify 1,148 base pair of E2 gene in extracted RNA and was sequenced using standard Sanger's sequencing. Phylogenetic analysis revealed the virus as genotype 2.2 that clustered with CSF virus sequences from Bangladesh and India. This is only the second report of a CSF outbreak in Bangladesh. CSF appears to be an emerging transboundary disease in this country. A special programme for controlling swine diseases is needed since pigs are being reared by marginalized communities of Bangladesh to provide livelihoods and food security.

中文翻译：

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孟加拉国库里格拉姆地区本地猪群再次爆发猪瘟。

2015 年 11 月中旬，孟加拉国库里格拉姆县 Nageswari 分区报告出现本地食腐猪死亡事件。对疑似猪瘟 (CSF) 疫情的调查是由孟加拉国畜牧服务部 (DLS) 和粮食及农业组织跨界动物疫病应急中心 (FAO-ECTAD) 联合疫情调查小组完成的。592头猪中，有396头被感染，其中263头死亡。发病率和病死率分别为66.9%和66.4%。利用从CSF爆发点捕获的数据构建的流行曲线接近钟形，表明点源流行。根据攻击率和指数增长率方法，基本繁殖数 (R0) 估计分别为 1.6（95% 置信区间 [CI]：1.5-1.7）和 1.5（95% CI：1.3-1.7）。成年猪表现出高烧、步态蹒跚和抑郁的症状，而仔猪则要么在没有任何先兆症状的情况下死亡，要么观察到眼睛中有脓性渗出物。对一头 6 个月大的仔猪进行了尸检。尸检结果包括深红色淋巴结肿大、肠道器官浆膜和粘膜出血以及肠道内纽扣样溃疡。使用实时逆转录酶聚合酶链反应（RT-qPCR）对鼻拭子和组织样本（脾、肺和肝）进行检测，发现脑脊液病毒呈阳性。使用一步 RT-PCR 扩增提取的 RNA 中 E2 基因的 1,148 个碱基对，并使用标准 Sanger 测序进行测序。系统发育分析显示该病毒的基因型为 2.2，与来自孟加拉国和印度的脑脊液病毒序列聚类。这只是孟加拉国第二次报告猪瘟疫情。脑脊液似乎是该国新出现的跨境疾病。由于孟加拉国边缘化社区饲养生猪以提供生计和粮食安全，因此需要制定控制猪病的特殊计划。