The bacterial growth cycle contains different phases: after the growth substrate is exhausted or the toxic waste products accumulate the growth stops. In this non-growing culture the number of colony forming bacteria remains constant or starts to decrease. It has been shown that during prolonged incubation there is constant growth and death of bacteria and certain mutant populations take over the culture. Here we show that the dynamic cell division and death balance can be obtained even before the appearance of mutants. The possible presence of different subpopulation should be considered when analyzing physiological states of bacterial cultures.

中文翻译：

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在固定阶段划分大肠杆菌亚群。

细菌的生长周期包含不同的阶段：在生长基质耗尽或有毒废物积聚后，生长停止。在这种不生长的培养物中，菌落形成细菌的数量保持恒定或开始减少。已经表明，在长时间的孵育过程中，细菌会不断生长和死亡，某些突变种群会接管培养物。在这里我们表明，即使在突变体出现之前，也可以获得动态细胞分裂和死亡平衡。分析细菌培养物的生理状态时，应考虑不同亚群的可能存在。