Circoviruses are small circular DNA viruses causing severe pig and poultry disease, recently identified in various bat species worldwide. We report the detection and full-genome molecular characterization of a novel bat-associated Circovirus identified in faecal samples of Miniopterus schreibersii bats (Schreiber's bent-winged bats) from Sardinia, Italy. Full-genomic sequencing revealed a new putative member of Circoviridae family, with a genome size of 2063 nt. Sequencing allowed the characterization of the two major ORFs, inversely arranged, encoding replicase and capsid proteins, as well as the finding of a polythymidine tract within the genome, and highlighted phylogenetic relationships of the novel virus. This is the first report of circovirus in European bats. Giving the high level of genetic diversity of bat circoviruses, it is paramount to further investigate the relationships between these viruses and bats.

中文翻译：

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在欧洲Miniopterus schreibersii蝙蝠中检测到的新型蝙蝠相关圆环病毒的基因组学表征。

圆环病毒是引起严重的猪和家禽疾病的小型环状DNA病毒，最近已在全球各种蝙蝠物种中鉴定出来。我们报告了在意大利撒丁岛的Miniopterus schreibersii蝙蝠（Schreiber的弯曲翅蝙蝠）的粪便样本中发现的新型蝙蝠相关圆环病毒的检测和全基因组分子表征。全基因组测序揭示了环状病毒科的一个新推定成员，其基因组大小为2063 nt。测序可以表征两个主要的ORF，它们反向排列，编码复制酶和衣壳蛋白，并在基因组中发现了聚胸苷束，并突出了新病毒的系统发育关系。这是欧洲蝙蝠中圆环病毒的首次报道。考虑到蝙蝠圆环病毒的高度遗传多样性，