Introduction: Current treatments for osteogenic disorders are often successful, however they are not free of drawbacks, such as toxicity or side effects. Nanotechnology offers a platform for drug delivery in the treatment of bone disorders, which can overcome such limitations. Nevertheless, traditional synthesis of nanomaterials presents environmental and health concerns due to its production of toxic by-products, the need for extreme and harsh raw materials, and their lack of biocompatibility over time.Areas covered: This review article contains an overview of the current status of treating osteogenic disorders employing green nanotechnological approaches, showing some of the latest advances in the application of green nanomaterials, as drug delivery carriers, for the effective treatment of osteogenic disorders.Expert opinion: Green nanotechnology, as a potential solution, is understood as the use of living organisms, biomolecules and environmentally friendly processes for the production of nanomaterials. Nanomaterials derived from bacterial cultures or biomolecules isolated from living organisms, such as carbohydrates, proteins, and nucleic acids, have been proven to be effective composites. These nanomaterials introduce enhancements in the treatment and prevention of osteogenic disorders, compared to physiochemically-synthesized nanostructures, specifically in terms of their improved cell attachment and proliferation, as well as their ability to prevent bacterial adhesion.

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基于绿色纳米技术的成骨疾病药物输送系统。

简介：当前针对成骨性疾病的治疗通常是成功的，但是它们也没有缺点，例如毒性或副作用。纳米技术为治疗骨骼疾病提供了平台，可以克服这些局限性。然而，由于其有毒副产物的产生，对极端和苛刻原材料的需求以及随着时间的推移它们缺乏生物相容性，传统的纳米材料合成仍然存在环境和健康问题。涵盖范围：本文概述了当前绿色纳米技术方法治疗成骨性疾病的现状，显示了绿色纳米材料作为药物递送载体在有效治疗成骨性疾病中的最新应用进展。专家意见：绿色纳米技术作为一种潜在的解决方案，被理解为利用生物体，生物分子和环保工艺生产纳米材料。从细菌培养物或从活生物体中分离出来的生物分子（例如碳水化合物，蛋白质和核酸）衍生的纳米材料已被证明是有效的复合材料。与物理化学合成的纳米结构相比，这些纳米材料在成骨性疾病的治疗和预防方面得到了增强，特别是在改善的细胞附着和增殖以及防止细菌粘附的能力方面。从细菌培养物或从活生物体中分离出来的生物分子（例如碳水化合物，蛋白质和核酸）衍生的纳米材料已被证明是有效的复合材料。与物理化学合成的纳米结构相比，这些纳米材料在成骨性疾病的治疗和预防方面得到了增强，特别是在改善的细胞附着和增殖以及防止细菌粘附的能力方面。从细菌培养物或从活生物体中分离出来的生物分子（例如碳水化合物，蛋白质和核酸）衍生的纳米材料已被证明是有效的复合材料。与物理化学合成的纳米结构相比，这些纳米材料在成骨性疾病的治疗和预防方面得到了增强，特别是在改善的细胞附着和增殖以及防止细菌粘附的能力方面。