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Mining the infant gut microbiota for therapeutic targets against atopic disease
Allergy ( IF 12.4 ) Pub Date : 2020-03-10 , DOI: 10.1111/all.14244
Rozlyn C T Boutin 1, 2 , Hind Sbihi 1, 3 , Melissa Dsouza 4 , Raunaq Malhotra 5 , Charisse Petersen 1, 2 , Darlene Dai 1, 3 , Malcolm R Sears 6 , Theo J Moraes 7 , Allan B Becker 8 , Meghan B Azad 8 , Piush J Mandhane 9 , Padmaja Subbarao 7 , B Brett Finlay 1, 2 , Stuart E Turvey 1, 3
Affiliation  

3. Andiappan AK, Sio YY, Lee B, et al. Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis. J Allergy Clin Immunol. 2016;137:758-766. 4. Miller M, Rosenthal P, Beppu A, et al. ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. J Immunol. 2014;192:3475-3487. 5. Miller M, Rosenthal P, Beppu A, Gordillo R, Broide DH. Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide. J Allergy Clin Immunol. 2017;139:1373-1376. 6. Soderman J, Berglind L, Almer S. Gene expression-genotype analysis implicates GSDMA, GSDMB, and LRRC3C as contributors to inflammatory bowel disease susceptibility. Biomed Res Int. 2015;2015:834805. 7. Wan YI, Shrine NR, Soler Artigas M, et al. Genome-wide association study to identify genetic determinants of severe asthma. Thorax. 2012;67:762-768. 8. Kang MJ, Yu HS, Seo JH, et al. GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness. Hum Immunol. 2012;73:954-959. 9. Berce V, Kozmus CE, Potocnik U. Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma. Pharmacogenomics J. 2013;13:523-529.

中文翻译:

挖掘婴儿肠道微生物群以寻找针对特应性疾病的治疗靶点

3. Andiappan AK、Sio YY、Lee B 等。17q12-21 的功能变体与过敏性哮喘有关,但与过敏性鼻炎无关。J 过敏临床免疫学。2016 年;137:758-766。4. 米勒 M、罗森塔尔 P、别府 A 等。ORMDL3 转基因小鼠具有增加的气道重塑和哮喘的气道反应性特征。J免疫学。2014;192:3475-3487。5. Miller M、Rosenthal P、Beppu A、Gordillo R、Broide DH。Oroscomucoid 样蛋白 3 (ORMDL3) 转基因小鼠的鞘脂水平降低,包括 1-磷酸鞘氨醇和神经酰胺。J 过敏临床免疫学。2017;139:1373-1376。6. Soderman J、Berglind L、Almer S. 基因表达-基因型分析表明 GSDMA、GSDMB 和 LRRC3C 是炎症性肠病易感性的因素。生物医学 Res Int。2015 年;2015 年:834805。7. Wan YI、Shrine NR、Soler Artigas M 等。全基因组关联研究,以确定严重哮喘的遗传决定因素。胸部。2012;67:762-768。8. Kang MJ、Yu HS、Seo JH 等。GSDMB/ORMDL3 变异导致哮喘易感性和嗜酸性粒细胞介导的支气管高反应性。嗡嗡声免疫。2012;73:954-959。9. Berce V、Kozmus CE、Potocnik U. ORMDL3 基因表达、17q21 多态性和哮喘儿童吸入皮质类固醇治疗反应之间的关联。药物基因组学杂志 2013;13:523-529。哮喘患儿的 17q21 多态性和对吸入性皮质类固醇治疗的反应。药物基因组学杂志。2013;13:523-529。哮喘患儿的 17q21 多态性和对吸入性皮质类固醇治疗的反应。药物基因组学杂志 2013;13:523-529。
更新日期:2020-03-10
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