A systematic review and network meta-analysis (NMA) were conducted to address the question, ‘What is the efficacy of litter management strategies to reduce morbidity, mortality, condemnation at slaughter, or total antibiotic use in broilers?’ Eligible studies were clinical trials published in English evaluating the efficacy of litter management in broilers on morbidity, condemnations at slaughter, mortality, or total antibiotic use. Multiple databases and two conference proceedings were searched for relevant literature. After relevance screening and data extraction, there were 50 trials evaluating litter type, 22 trials evaluating litter additives, 10 trials comparing fresh to re-used litter, and six trials evaluating floor type. NMAs were conducted for mortality (61 trials) and for the presence or absence of footpad lesions (15 trials). There were no differences in mortality among the litter types, floor types, or additives. For footpad lesions, peat moss appeared beneficial compared to straw, based on a small number of comparisons. In a pairwise meta-analysis, there was no association between fresh versus used litter on the risk of mortality, although there was considerable heterogeneity among studies (I2 = 66%). There was poor reporting of key design features in many studies, and analyses rarely accounted for non-independence of observations within flocks.

中文翻译：

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垫料管理策略预防肉鸡发病率和死亡率的有效性：系统评价和网络荟萃分析

进行了系统回顾和网络荟萃分析 (NMA) 来解决这个问题，“垫料管理策略在降低肉鸡的发病率、死亡率、屠宰淘汰或抗生素总使用量方面的效果如何？” 符合条件的研究是用英文发表的临床试验，评估垫料管理对肉鸡的发病率、屠宰时的谴责、死亡率或抗生素使用总量的效果。检索了多个数据库和两个会议论文集以查找相关文献。在相关性筛选和数据提取后，有 50 项试验评估垫料类型，22 项试验评估垫料添加剂，10 项试验比较新鲜和重复使用的垫料，6 项试验评估地板类型。对死亡率（61 项试验）和是否存在足垫病变（15 项试验）进行了 NMA。垫料类型、地板类型或添加剂之间的死亡率没有差异。基于少量比较，对于足垫病变，泥炭苔似乎比稻草有益。在成对的荟萃分析中，新鲜和使用过的垫料与死亡风险之间没有关联，尽管研究之间存在相当大的异质性。一世2= 66%）。许多研究中对关键设计特征的报道很差，分析很少解释鸡群内观察的非独立性。