Clinical Characteristics and Outcomes of invasive Lomentospora prolificans Infections: Analysis of Patients in the FungiScope® Registry,Mycoses

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Clinical Characteristics and Outcomes of invasive Lomentospora prolificans Infections: Analysis of Patients in the FungiScope® Registry
Mycoses ( IF 4.9 ) Pub Date : 2020-04-15 , DOI: 10.1111/myc.13067
Jeffrey D Jenks _{1,

2} , Danila Seidel ₃ , Oliver A Cornely ₃ , Sharon Chen ₄ , Sebastiaan van Hal ₅ , Carol Kauffman ₆ , Marisa H Miceli ₆ , Melina Heinemann ₇ , Martin Christner ₈ , Alfredo Jover Sáenz ₉ , Alexander Burchardt ₁₀ , Björn Kemmerling ₁₀ , Raoul Herbrecht ₁₁ , Joerg Steinmann _{12,

13} , Shmuel Shoham ₁₄ , Sandra Gräber ₁₅ , Livio Pagano ₁₆ , Dries Deeren ₁₇ , Monica A Slavin ₁₈ , Martin Hoenigl _{1,

2,

19}

Affiliation

Department of Medicine, University of California San Diego, San Diego, CA, USA.
Clinical and Translational Fungal Research Group, University of California San Diego, San Diego, CA, USA.
Department I of Internal Medicine, ECMM Excellence Centre of Medical Mycology, CECAD-Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University Hospital Cologne, Cologne, Germany.
Sydney Medical School, Centre for Infectious Diseases and Microbiology, Westmead Hospital, The University of Sydney, Camperdown, New South Wales, Australia.
Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Territorial Unit of Nosocomial Infection and antibiotic policy (TUNI), University Hospital Arnau de Vilanova, Lleida, Spain.
Department of Hematology, Hospital of Justus Liebig University, Giessen, Germany.
Department of Oncology and Hematology, Strasbourg University Hospital, Strasbourg, France.
Institute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.
Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Institute of Medical Microbiology and Epidemiology of Infectious Diseases, University Hospital Leipzig, Leipzig, Germany.
Department of Hematology, Fondazione Policlinico A. Gemelli - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Department of Hematology, AZ Delta, Roeselare, Belgium.
Department of Infectious Diseases, Peter MacCallum Cancer Centre, National Centre for Infections in Cancer, Melbourne, Vic., Australia.
Department of Medicine, ECMM Excellence Centre of Medical Mycology, Medical University of Graz, Graz, Austria.

Invasive fungal infections caused by Lomentospora prolificans are associated with very high mortality rates and can be challenging to treat given pan‐drug resistance to available antifungal agents. The objective of this study was to describe the clinical presentation and outcomes in a cohort of patients with invasive L prolificans infections.

中文翻译：

侵袭性多产 Lomentospora 感染的临床特征和结果：FungiScope® Registry 中的患者分析

由多产 Lomentospora 引起的侵袭性真菌感染与非常高的死亡率相关，并且在对现有抗真菌剂的泛耐药性的情况下治疗可能具有挑战性。本研究的目的是描述一组侵袭性多产 L 型感染患者的临床表现和结果。

更新日期：2020-04-15

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