Epilepsy surgery is the most effective treatment option for children with refractory focal lesional epilepsy, with seizure-freedom rates exceeding 70% two years after surgery. Although numbers of procedures in children are increasing over time, epilepsy surgery remains underutilized. Particularly in young children with developmental delay, arrest, or even regression, surgery can improve cognitive outcome. Many factors determine eventual developmental abilities, of which epilepsy duration is the most important modifiable predictor. Earlier surgery is not only associated with higher seizure-freedom rates, it also improves postoperative developmental outcomes. Every child with focal lesional epilepsy should therefore be referred early, to evaluate the possibilities of epilepsy surgery.

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癫痫手术对儿童发育结局的影响

癫痫手术是儿童难治性局灶性病灶性癫痫最有效的治疗选择，手术后两年无癫痫发作率超过 70%。尽管儿童手术的数量随着时间的推移而增加，但癫痫手术仍未得到充分利用。特别是在发育迟缓、停滞甚至退化的幼儿中，手术可以改善认知结果。许多因素决定了最终的发育能力，其中癫痫持续时间是最重要的可改变预测因素。早期手术不仅与更高的无癫痫发作率相关，还可以改善术后发育结果。因此，每个患有局灶性病灶性癫痫的儿童都应尽早转诊，以评估癫痫手术的可能性。