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Less enhancement and low apparent diffusion coefficient value on magnetic resonance imaging may be helpful to detect canine prostate adenocarcinoma in case series.
Veterinary and Comparative Oncology ( IF 2.1 ) Pub Date : 2020-02-12 , DOI: 10.1111/vco.12578
Toshiyuki Tanaka 1, 2 , Kazuna Ashida 1 , Yasumasa Iimori 1 , Hiroki Yamazaki 1 , Keiichiro Mie 1 , Hidetaka Nishida 1 , Hideo Akiyoshi 1
Affiliation  

In dogs, diagnosis of prostate cancer is often delayed because clinical signs are not pathognomonic. Although ultrasonography is mainly performed to detect prostate cancer, the ultrasonographic appearance is not specific. In humans, magnetic resonance imaging (MRI), including diffusion‐weighted imaging (DWI) is used to localize the prostate tumour. To our knowledge, there are no studies of MRI findings for detecting or localizing prostate cancer. The purpose of this study was to assess MRI findings of prostate cancer. As a control, three prostate hyperplasia cases were included. MRI data were analysed, and the following parameters were noted: signal intensity (SI) of prostate lesion on T2‐weighted imaging, T1‐weighted imaging and DWI, enhancement pattern of prostate lesion, and relative contrast enhancement indices (RCEI) and apparent diffusion coefficient (ADC) value of prostate lesion. For MRI examination, the mean RCEI of the adenocarcinoma was significantly lower than that of hyperplasia (P = .01, r = .8). The SI of the DWI of adenocarcinoma was significantly higher compared to hyperplasia (P = .03, φ = 1). The mean ADC values of the adenocarcinoma were significantly lower than that of hyperplasia (P = .03, r = .82). Thus, less enhancement on MRI, and low ADC value on MRI may help to detect prostate adenocarcinoma.

中文翻译:

磁共振成像上增强较少和表观扩散系数值较低可能有助于在病例系列中检测犬前列腺腺癌。

在狗中,前列腺癌的诊断经常被延迟,因为临床症状不是特异性的。虽然超声检查主要用于检测前列腺癌,但超声检查的表现并不具有特异性。在人类中,包括弥散加权成像 (DWI) 在内的磁共振成像 (MRI) 用于定位前列腺肿瘤。据我们所知,目前还没有关于 MRI 发现用于检测或定位前列腺癌的研究。本研究的目的是评估前列腺癌的 MRI 结果。作为对照,包括三个前列腺增生病例。分析 MRI 数据,并记录以下参数:T2 加权成像、T1 加权成像和 DWI 上前列腺病变的信号强度(SI)、前列腺病变的增强模式、前列腺病变的相对对比度增强指数(RCEI)和表观扩散系数(ADC)值。对于MRI检查,腺癌的平均RCEI显着低于增生的RCEI(P = .01,r = .8)。与增生相比,腺癌的 DWI 的 SI 显着更高(P = .03,φ = 1)。腺癌的平均 ADC 值显着低于增生的 ( P = .03, r = .82)。因此,MRI 的增强较少和 MRI 的 ADC 值低可能有助于检测前列腺癌。
更新日期:2020-02-12
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