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Plant NLR-triggered immunity: from receptor activation to downstream signaling.
Current Opinion in Immunology ( IF 7 ) Pub Date : 2020-01-17 , DOI: 10.1016/j.coi.2019.12.007
Signe Lolle 1 , Danielle Stevens 2 , Gitta Coaker 1
Affiliation  

Innate immune perception is the first line of inducible defense against invading pathogens. Plants lack specialized circulating immune cells. Therefore, diverse cell types are able to recognize and respond to pathogens. Surface-localized and intracellular plant innate immune receptors are capable of recognizing diverse pathogen components. Intracellular nucleotide-binding leucine-rich repeat (NLR) receptors recognize pathogen effectors delivered inside host cells. Recent advances shed light onto NLR activation, phosphorylation of defense signaling nodes and overlap in transcriptional responses between pathogen perception and abiotic stress.

中文翻译:

植物 NLR 触发的免疫:从受体激活到下游信号。

先天免疫感知是抵御入侵病原体的第一道诱导防御线。植物缺乏专门的循环免疫细胞。因此,不同的细胞类型能够识别病原体并对其作出反应。表面定位和细胞内植物先天免疫受体能够识别多种病原体成分​​。细胞内核苷酸结合的富含亮氨酸重复序列 (NLR) 受体识别宿主细胞内传递的病原体效应物。最近的进展揭示了 NLR 激活、防御信号节点的磷酸化以及病原体感知和非生物胁迫之间转录反应的重叠。
更新日期:2020-01-17
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