The title benzothiazine-3-carboxamide, C17H16N2O4S, crystallized in two enantiomorphic crystal forms with the space groups P32 and P31 despite the absence of a classic stereogenic atom. The molecular structures are mirror images of each other. Only one sulfonyl O atom takes part in intramolecular hydrogen bonding as a proton acceptor and this atom is different in the two enantiomorphic structures. As a result, the S atom becomes a pseudo-stereogenic centre. This fact is worth taking into account due to the different biological activities of the enantiomorphic forms. One form possesses a high analgesic activity, while the other form revealed a high anti-inflammatory activity.

中文翻译：

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N-（2,6-二甲基苯基）-4-羟基-2,2-二氧代-1H-2λ6,1-苯并噻嗪-3-羧酰胺（吡罗昔康的结构类似物）的两种对映体形式的生物学特性。

标题苯并噻嗪-3-羧酰胺C17H16N2O4S结晶为两种对映体晶型，空间群为P32和P31，尽管没有经典的立体原子。分子结构是彼此的镜像。仅有一个磺酰基O原子作为质子受体参与分子内氢键，并且该原子在两个对映体结构上不同。结果，S原子成为假立体中心。由于对映体形式的生物活性不同，这一事实值得考虑。一种形式具有较高的镇痛活性，而另一种形式具有较高的抗炎活性。