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Studying neural circuits of decision-making in Drosophila larva.
Journal of Neurogenetics ( IF 1.9 ) Pub Date : 2020-02-13 , DOI: 10.1080/01677063.2020.1719407
Tihana Jovanic 1, 2
Affiliation  

To study neural circuits underlying decisions, the model organism used for that purpose has to be simple enough to be able to dissect the circuitry neuron by neuron across the nervous system and in the same time complex enough to be able to perform different types of decisions. Here, I lay out the case: (1) that Drosophila larva is an advantageous model system that balances well these two requirements and (2) the insights gained from this model, assuming that circuit principles may be shared across species, can be used to advance our knowledge of neural circuit implementation of decision-making in general, including in more complex brains.

中文翻译:

研究果蝇幼虫决策的神经回路。

为了研究决策背后的神经回路,用于该目的的模型生物必须足够简单,以便能够在整个神经系统中逐个神经元解剖回路,同时足够复杂以能够执行不同类型的决策。在这里,我提出了一个案例:(1) 果蝇幼虫是一个有利的模型系统,它很好地平衡了这两个要求;(2) 从这个模型中获得的见解,假设电路原理可以在物种之间共享,可用于推进我们对一般决策的神经回路实现的知识,包括在更复杂的大脑中。
更新日期:2020-02-13
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