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Review of Clinically and Epidemiologically Relevant Coagulase-Negative Staphylococci in Africa.
Microbial Drug Resistance ( IF 2.6 ) Pub Date : 2020-07-31 , DOI: 10.1089/mdr.2019.0381
Jonathan Asante 1, 2 , Daniel G Amoako 1 , Akebe L K Abia 1 , Anou M Somboro 2, 3 , Usha Govinden 1 , Linda A Bester 3 , Sabiha Y Essack 1
Affiliation  

Coagulase-negative staphylococci (CoNS) have engendered substantial interest in recent years as pathogenic causes of infections in both human and veterinary medicine, especially in the immunocompromised, critically ill, long-term hospitalized and in those harboring invasive medical devices such as catheters. They have been implicated in infections such as urinary tract infections, bloodstream infections, and invasive device-related infections, and are responsible for substantial economic losses in livestock production. The advancement of diagnostic techniques has increased our understanding of their molecular mechanisms of pathogenicity, even though distinguishing between innocuousness and pathogenicity is still challenging.

中文翻译:

非洲临床和流行病学相关的凝固酶阴性葡萄球菌综述。

近年来,凝固酶阴性葡萄球菌(CoNS)作为引起人类和兽医感染的致病原因,尤其是免疫功能低下,危重病,长期住院以及那些带有侵入性医疗器械(如导管)的感染引起了人们的极大兴趣。它们与尿路感染,血流感染和侵入性器械相关感染等感染有关,是造成牲畜生产大量经济损失的原因。诊断技术的进步使我们更加了解其致病性的分子机制,尽管区分无毒和致病性仍然具有挑战性。
更新日期:2020-08-08
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