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Interventional Radiological Treatment of Paediatric Liver Transplantation Complications.
CardioVascular and Interventional Radiology ( IF 2.9 ) Pub Date : 2020-02-10 , DOI: 10.1007/s00270-020-02430-8
Jan H Peregrin 1 , Jozef Kováč 1 , Martin Prchlík 2 , Pavel Heinige 2 , Radana Kotanová 3 , Jiří Froňek 4 , Róbert Novotný 4 , Matěj Kočík 4 , Libor Janoušek 5
Affiliation  

PURPOSE To assess the efficacy of percutaneous techniques in managing paediatric liver transplantation complications. MATERIAL AND METHODS We carried out 105 paediatric cadaveric donor liver transplantations at our centre from 2001 to 2018. Percutaneous techniques were used to treat 25 cases involving transplantation complications in 23 patients. Biliary complications were treated in 14 cases (13.3%): 10 patients had bile duct obstruction, and 4 had biliary leaks. Vascular complications were treated in 11 cases (10.5%): 5 hepatic artery (HA) stenoses/occlusions, 2 inferior vena cava (IVC) stenoses, and 1 portal vein (PV) stenosis. Other interventions involved embolisation of the superior mesenteric artery branch to manage gastrointestinal bleeding in 2 patients and embolisation of an arteriobiliary fistula in 1 patient. RESULTS Biliary: We carried out external-internal drainage and balloon dilatation of stenoses in 12 cases. The external-internal drainage catheter was removed after 6-8 weeks in 7 patients, with the remaining 5 patients with persisting stenosis assigned for retransplantation. We failed to cross anastomotic occlusions in 2 patients before completing the procedures using external drainage; both individuals subsequently underwent retransplantation. Vascular: We performed PTA/stenting of HA stenoses/occlusions in 4 out of 5 patients. After the procedure, all 4 patients showed liver function normalisation. All 3 cases of embolisation were technically and clinically successful. Both IVC and PV stenoses treated with dilatation/stenting were also successful. CONCLUSIONS Percutaneous techniques used to treat biliary and vascular complications after liver transplantation in paediatric patients are safe and efficient.

中文翻译:

小儿肝移植并发症的介入放射治疗。

目的评估经皮技术在处理小儿肝移植并发症中的功效。材料与方法2001年至2018年,我们在中心进行了105例小儿尸体供体肝移植。使用经皮技术治疗了25例涉及移植并发症的病例,其中23例患者。胆道并发症14例(13.3%):胆管阻塞10例,胆漏4例。血管并发症的治疗11例(10.5%):5例肝动脉(HA)狭窄/闭塞,2例下腔静脉(IVC)狭窄和1例门静脉(PV)狭窄。其他干预措施包括栓塞肠系膜上动脉分支栓塞以治疗2例胃肠道出血和1例栓塞动胆瘘。结果胆道:我们对狭窄进行了内外引流和狭窄的球囊扩张术12例。7例患者在6-8周后拔出了内外引流导管,其余5例患有持续狭窄的患者被指定进行移植。在使用外部引流完成手术之前,我们没有对2例患者进行吻合口吻合;两个人随后都进行了移植。血管:我们对5名患者中的4名进行了PTA / HA狭窄/支架狭窄的支架置入术。手术后,所有4例患者均显示肝功能正常化。3例栓塞术在技术和临床上均成功。经扩张/支架置入的IVC和PV狭窄也都成功。
更新日期:2020-02-10
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