Poincianella bracteosa

(Tul.) L.P. Queiroz. (Fabaceae) traditionally is used in Brazilian medicine to treat catarrhal infections, diarrhea, hepatitis and anemia. We investigated the phytochemical profile, and mutagenicity and anti-mutagenicity of aqueous extracts of leaves of P. bracteosa in A. cepa cells and in mice. We investigated four concentrations of extract for the A. cepa bioassay and three doses of extract for administration to mice. For the A. cepa assay, we analyzed 5,000 meristematic cells to determine the mitotic index, mean number of chromosome alterations and percentage of damage reduction. For each animal assay, 2,000 normochromatic erythrocytes were evaluated per mouse to determine the number of micronuclei and the protective effect of the extract. Phytochemical analysis of the extract revealed reducing sugars, tannins and alkaloids, which likely did not interfere with the cell cycle of A. cepa or cause damage to the DNA of A. cepa or mice. The extract exhibited a protective effect in both organisms.

中文翻译：

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评价Poincianella bracteosa（Tul。）LP Queiroz叶片对葱属和小家鼠的作用。

inc菜

（塔尔。）LP Queiroz。（豆科）传统上在巴西医学中用于治疗卡他性感染，腹泻，肝炎和贫血。我们研究了植物化学的空间，致突变性和叶的水提取物的抗诱变P. bracteosa在圆葱细胞和小鼠。我们调查了四种浓度的提取物用于A. cepa生物测定，并研究了三剂提取物的给药剂量。对于A. cepa分析中，我们分析了5,000个分生组织细胞，以确定有丝分裂指数，染色体平均改变数和损伤减少百分比。对于每种动物试验，每只小鼠评估2,000个常色红细胞，以确定微核的数量和提取物的保护作用。提取物的植物化学分析表明，还原糖，单宁和生物碱可能不会干扰洋葱曲霉的细胞周期或不会破坏洋葱曲霉或小鼠的DNA 。提取物对两种生物均显示出保护作用。