Mesenchymal stem cells (MSCs) are multipotent cells that are excellent candidates for different cellular therapies due to their physiological properties such as immunoregulatory function. whetheare currently utilized for regenerative medication and treatment of a number of inflammatory illnesses given their ability to considerably impact tissue microenvironments via extracellular vesicles or toll-like receptor pathway modulation. MicroRNAs (miRNAs) are small noncoding RNAs that target the messenger RNA and play a critical role in different biological procedures, such as the development and reaction of the immune system. Moreover, miRNAs have recently been revealed to have serious functions in MSCs to regulate immunomodulatory properties. In this review, we study how the miRNAs pathway can modulate the immunoregulatory activity of MSCs by counting their interactions with immune cells and also discuss the possibility of using miRNA-based implications for MSC-based therapies.

中文翻译：

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间充质干细胞的免疫调节特性：微小RNA。

间充质干细胞（MSC）是多能细胞，由于它们的生理特性（例如免疫调节功能），因此是不同细胞疗法的极佳候选者。由于它们具有通过细胞外囊泡或通行费样受体途径调节显着影响组织微环境的能力，因此目前被用于再生药物和多种炎性疾病的治疗。MicroRNA（miRNA）是靶向信使RNA的小型非编码RNA，并且在不同的生物学程序（例如免疫系统的发育和反应）中起关键作用。而且，最近发现miRNA在MSC中具有严重的功能以调节免疫调节特性。在这篇评论中