Local field potentials evoked by body action and mental action verbs were recorded in the subthalamic nucleus (STN) of 18 patients with Parkinson's disease through the electrodes implanted for deep brain stimulation. Compared with the medication on-condition, the medication off-condition showed a difference in activity in the early time segments, mainly in the right STN, with larger amplitudes for body action verbs. In the on-condition a similar pattern was detected in the left STN. These patterns of early differences in activity evoked by different types of verbs might indicate the potential of the STN to rapidly detect relevant behavioural clues in verbal content and to integrate these in subsequent cortico-subcortical interactions. In addition, these lateralizations allow speculations about shifts in processing activity correlating with dopaminergic denervation. Whether this detection relies on phonological, semantic or grammatical clues remains an open question.

中文翻译：

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丘脑底核活动在帕金森病患者身体和心理动作动词的加工中

通过植入深部脑刺激电极，在18例帕金森病患者的丘脑底核（STN）中记录了身体动作和精神动作动词诱发的局部场电位。与药物状态相比，药物关闭状态在早期时间段表现出活动的差异，主要是在右侧 STN 中，身体动作动词的幅度更大。在开启条件下，在左侧 STN 中检测到类似的模式。这些由不同类型动词引起的早期活动差异模式可能表明 STN 具有快速检测语言内容中相关行为线索并将这些线索整合到随后的皮质-皮质下相互作用中的潜力。此外，这些偏侧化允许推测与多巴胺能去神经支配相关的加工活动的变化。这种检测是否依赖于语音、语义或语法线索仍然是一个悬而未决的问题。