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Association Between Somatization and Nonmotor Symptoms Severity in People With Parkinson Disease.
Journal of Geriatric Psychiatry and Neurology ( IF 2.6 ) Pub Date : 2020-02-06 , DOI: 10.1177/0891988720901787
Aranza Polo-Morales 1, 2 , Ángel Alcocer-Salas 2 , Mayela Rodríguez-Violante 2, 3 , Daniella Pinto-Solís 2, 4 , Rodolfo Solís-Vivanco 5 , Amin Cervantes-Arriaga 2, 3
Affiliation  

OBJECTIVE To assess the frequency of somatization and its association with motor, nonmotor symptoms, and quality of life in persons with Parkinson disease (PD). METHODS A cross-sectional case-control study was carried out. Assessments included the List of 90 Symptoms somatic factor (SCL-90-R SOM), Movement Disorder Society Unified Parkinson's Ratings Scale (MDS-UPDRS), Non-Motor Symptom Scale (NMSS), Montreal Cognitive Assessment (MoCA), and Parkinson Questionnaire-8 (PDQ-8). RESULTS A total 93 persons with PD and 93 controls were included. Somatization within the PD group was 2 times more frequent compared to the control group (43% vs 21.5%, P = .003). Persons with PD had higher NMSS total scores (48.6 ± 42.6 vs 28.3 ± 30.4, P = .001). Patients with PD with somatization had worst MDS-UPDRS, NMSS, MoCA, and PDQ-8 (all P < .05). CONCLUSION Somatization is more frequent in persons with PD compared to healthy controls. Somatization in PD is associated with nonmotor symptoms and worst quality of life.

中文翻译:

帕金森病患者的躯体化与非运动症状严重程度之间的关联。

目的评估帕金森病(PD)患者的躯体化频率及其与运动,非运动症状和生活质量的关系。方法进行横断面病例对照研究。评估包括90种症状的躯体因素(SCL-90-R SOM),运动障碍学会统一帕金森氏量表(MDS-UPDRS),非运动症状量表(NMSS),蒙特利尔认知评估(MoCA)和帕金森问卷调查表-8(PDQ-8)。结果总共包括93名PD患者和93名对照。与对照组相比,PD组的躯体化频率高出2倍(43%比21.5%,P = 0.003)。PD患者的NMSS总分较高(48.6±42.6 vs 28.3±30.4,P = .001)。患有躯体化的PD患者的MDS-UPDRS,NMSS,MoCA和PDQ-8最差(所有P <.05)。结论与健康对照组相比,PD患者的躯体化更为频繁。PD的躯体化与非运动症状和最差的生活质量有关。
更新日期:2020-04-21
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