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When non-coding is not enough
The Journal of Experimental Medicine Pub Date : 2020-02-05 , DOI: 10.1084/jem.20192009
Simone Anfossi , George A Calin 1
Affiliation  

A new concept is emerging in the non-coding RNA (ncRNA) field: an increasing number of ncRNAs in fact codify for short peptides that have biological activities. In this issue of JEM, Wang et al. (https://doi.org/10.1084/jem.20190950) report the identification of a long ncRNA (lncRNA)–encoded 60–amino acid polypeptide that they name ASRPS, as well as its ability to inhibit angiogenesis in the deadly triple-negative breast cancer (TNBC).

中文翻译:

当非编码还不够时

非编码 RNA (ncRNA) 领域正在出现一个新概念:越来越多的 ncRNA 实际上编码具有生物活性的短肽。在本期《JEM》中,Wang 等人。(https://doi.org/10.1084/jem.20190950) 报告了一种长 ncRNA (lncRNA) 编码的 60 个氨基酸多肽的鉴定,他们将其命名为 ASRPS,以及它在致命的三重疾病中抑制血管生成的能力。阴性乳腺癌(TNBC)。
更新日期:2020-02-05
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