Objectives: To compare the efficacy and safety of anterior temporal lobotomy (ATLo) and anterior temporal lobectomy (ATLe) in drug-resistant temporal lobe epilepsy.Methods: Patients diagnosed with pharmacoresistant temporal lobe epilepsy who underwent anterior temporal lobotomy (ATLo) or anterior temporal lobectomy (ATLe) performed by a single surgeon were retrospectively included. Every patient was followed up annually after surgery. The postoperative seizure outcome evaluation was based on the Engel and ILAE classifications. We compared postoperative complications and 2-year follow-up seizure outcomes between the ATLo group and the ATL group.Results: A total of 42 individuals (21 ATLo and 20 ATLe) were included. At the two-year follow-up, more patients in the ATLo group than the ATLe group had reached Engel class I (20 versus 14) and ILAE I (19 versus 13). However, these differences were not significant. One patient in the ATLo group had intraparenchymal hematoma and fully recovered. The two groups had similar incidences of other short-term complications, and no patients died or had any permanent complications.Discussion: ATLo is not inferior to ATLe for patients with drug-resistant temporal epilepsy. There was no significant difference in seizure outcomes or the rate of postoperative complications between the two groups. A large sample randomized control study is needed.

中文翻译：

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颞叶癫痫患者前颞叶切除与肺叶切除术的癫痫发作结局和安全性比较。

目的：比较前颞叶切除术（ATLo）和前颞叶切除术（ATLe）在耐药性颞叶癫痫中的疗效和安全性。回顾性地包括由单个外科医生进行的肺叶切除术（ATLe）。手术后每年对所有患者进行随访。术后癫痫预后评估基于Engel和ILAE分类。我们比较了ATLo组和ATL组的术后并发症和2年随访癫痫发作的结果。结果：总共包括42例患者（21例ATLo和20例ATLe）。在两年的随访中，ATLo组的患者比达到Engel I类（20对14）和ILAE I（19对13）的患者多。但是，这些差异并不明显。ATLo组中的一名患者发生实质内血肿并完全康复。两组其他短期并发症的发生率相似，无患者死亡或任何永久性并发症。讨论：对于耐药性暂时性癫痫患者，ATLo不逊于ATLe。两组的癫痫预后或术后并发症发生率无显着差异。需要进行大样本随机对照研究。讨论：耐药性暂时性癫痫患者ATLo不逊于ATLe。两组的癫痫预后或术后并发症发生率无显着差异。需要进行大样本随机对照研究。讨论：耐药性暂时性癫痫患者ATLo不逊于ATLe。两组的癫痫预后或术后并发症发生率无显着差异。需要进行大样本随机对照研究。