Stem cells from human exfoliated deciduous teeth (SHED) have now been considered one of the most promising sources of stem cells for tissue engineering and stem cell therapies due to their stemness and potential to differentiate into other cell lines. The high proliferation rate, the differentiation capacity, the easy access and less ethical concerns make SHED a brilliant solution for many diseases. The purpose of this review is to describe current knowledge of SHED’s capability of differentiation, applications and immune status and to draw attention to further research on the mechanism and the dependability of stem cell therapy with SHED.

中文翻译：

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乳牙脱落干细胞的多向分化及临床应用[J].

来自人类脱落的乳牙 (SHED) 的干细胞由于其干性和分化成其他细胞系的潜力，现已被认为是用于组织工程和干细胞治疗的最有希望的干细胞来源之一。高增殖率、分化能力、易于获取和较少的伦理问题使 SHED 成为许多疾病的出色解决方案。这篇综述的目的是描述目前对SHED分化能力、应用和免疫状态的认识，并引起人们对SHED干细胞治疗机制和可靠性的进一步研究。