The development of earlier and less invasive treatments for peripheral arterial disease requires a more complete understanding of vascular responses following a major arterial occlusion. A mechanistic model of the vasculature of the rat hindlimb is developed to predict acute (immediate) changes in vessel diameters and smooth muscle tone following femoral arterial occlusion.

中文翻译：

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模拟对主要动脉闭塞的急性血流反应。

早期和较少侵入性的外周动脉疾病治疗方法的发展要求对大动脉闭塞后的血管反应有更全面的了解。建立了大鼠后肢脉管系统的机械模型，以预测股动脉闭塞后血管直径和平滑肌张力的急性（立即）变化。