It is almost 40 years since Barry Marshal and Robin Warrens identified and recovered Helicobacter pylori (H. pylori) from gastric biopsy specimens. They later demonstrated the role of H. pylori in peptic ulcers and in 2005, they were awarded the Nobel Prize in medicine for these groundbreaking discoveries. Later, it became clear that H. pylori has a carcinogenic role and the fact that a course of antibiotics influenced cancer occurrence was truly a "game changer".

中文翻译：

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感染及其在癌症发展中的作用。

自Barry Marshal和Robin Warrens从胃活检标本中鉴定出幽门螺杆菌（H. pylori）以来，已经过去了40年。他们后来证明了幽门螺杆菌在消化性溃疡中的作用，并于2005年因这些突破性发现而获得了诺贝尔医学奖。后来，很明显幽门螺杆菌具有致癌作用，而抗生素疗程影响癌症发生的事实确实是“改变游戏规则”的事实。