Ochratoxin A is one of the most diffused mycotoxin present in a large spectrum of food commodities, mainly produced by Aspergillus ochraceus, Aspergillus carbonarius, Aspergillus niger and Penicillium verrucosum. EU has set maximum limits for a number of matrices such as cereals, wine, spices and liquorice, whilst other commodities such as beer and meat products that are susceptible of OTA contamination and are largely consumed are not included. In 2013, within the framework of the Regulation (EC) 882/2004 on official controls, the European Commission issued the mandate M/520 regarding the standardisation for methods of analysis for mycotoxins in food to the European Committee for Standardisation. Of the 11 priorities of the mandate, the one on “HPLC determination of OTA in meat, meat products and edible offal” was assigned to the Italian National Reference Laboratory for feed and food. The method was single-laboratory validated, and all the performance characteristics of the method were compliant with the corresponding reference values indicated in Regulation (EC) n. 401/2006. The method was applied to characterise a set of 5 pork-based materials (ham, kidney, liver and canned chopped pork) to be used for an inter-laboratory method validation study. Three ham materials (levels of contamination of 0.77, 2.22 and 12.3 μg/kg, respectively), one liver material (contamination level of 2.80 μg/kg) and one chopped pork meat (contamination level of 0.66 μg/kg) were tested for homogeneity and stability.

中文翻译：

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猪肉制品中曲霉毒素A的测定：单一实验室验证方法和均质批料的制备。

赭曲霉毒素A是最普及的存在于大范围的食品的商品，主要由所产生的真菌毒素的一个赭曲霉，黑曲霉炭黑，黑曲霉和青霉疣状。欧盟已为谷物，葡萄酒，香料和甘草等多种基质设定了最高限量，而其他易受OTA污染并大量消费的商品（如啤酒和肉类产品）则不包括在内。2013年，在关于官方控制的（EC）882/2004法规的框架内，欧洲委员会向欧洲标准化委员会发布了有关食品中真菌毒素分析方法标准化的任务授权M / 520。在任务的11项优先重点中，一项关于“肉类，肉类产品和可食用内脏中OTA的HPLC测定”的工作被分配给了意大利国家饲料和食品参考实验室。该方法已通过单实验室验证，并且该方法的所有性能特征均符合法规（EC）n中指示的相应参考值。401/2006。该方法用于表征5种以猪肉为基础的材料（火腿，肾脏，肝脏和切碎的猪肉罐头），用于实验室间方法验证研究。测试了三种火腿材料（污染水平分别为0.77、2.22和12.3μg/ kg），一种肝脏材料（污染水平为2.80μg/ kg）和一种切碎的猪肉（污染水平为0.66μg/ kg）的同质性。和稳定性。