Objective: ADHD potentially leads to risky sexual behaviors, and is considered a major risk factor for early pregnancy (EP). However, the association between ADHD and subsequent EP remains unknown. Method: Seven thousand five hundred five adolescents with ADHD and 30,020 age- and sex-matched individuals without ADHD were enrolled from 2001 to 2009 and were followed until the end of 2011. Adolescents who developed any pregnancy (at age ≤30 years) or EP (at age <20 years) during the follow-up period were identified. Results: Adolescents with ADHD were found to be prone to pregnancy (hazard ratio [HR] = 1.27) and EP (HR = 2.30) compared with those without ADHD. Long-term ADHD medication use was related to a lower risk of subsequent any pregnancy (HR = 0.72) and EP (HR = 0.69). Conclusion: Adolescents with ADHD had an increased risk of any pregnancy and EP compared with their non-ADHD counterparts. Long-term ADHD medication use was associated with a lower subsequent EP risk.

中文翻译：

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多动症青少年的早期妊娠风险：一项全国纵向研究。

目的：多动症可能导致危险的性行为，被认为是早孕的主要危险因素。然而，ADHD与随后的EP之间的关联仍然未知。方法：从2001年至2009年，招募了755名患有ADHD的青少年和30,020名年龄和性别相匹配的无ADHD的青少年，并随访至2011年底。有怀孕（≤30岁）或EP的青少年随访期间（年龄<20岁）。结果：与没有ADHD的青少年相比，发现患有ADHD的青少年容易怀孕（危险比[HR] = 1.27）和EP（HR = 2.30）。长期使用ADHD药物与以后再怀孕（HR = 0.72）和EP（HR = 0.69）的风险较低有关。结论：与非ADHD青少年相比，患有ADHD的青少年发生任何妊娠和EP的风险均增加。长期使用ADHD药物可降低随后的EP风险。