Astaxanthin is a powerful carotenoid antioxidant prevalent in marine organisms and approved as a food supplement. Recent studies have demonstrated Astaxanthin’s beneficial attributes in various health states. Following initial reports of potential heat protective properties in Astaxanthin supplemented rats, we present here results of a novel study examining the effect of Astaxanthin supplementation on the heat shock response in rats in relation to core temperature (Tc) and the ensuing physiological strain. Two hours of heat stress at 41 °C during which rats developed their thermoregulatory hyperthermic plateau resulted in progressive increases in HSP72 and HSP27 in the Astaxanthin (Oleoresin)-treated group but not in the control (Olive oil) group. Enhanced elevation in HSPs suggests that Astaxanthin supplementation may augment the cellular stress protective response to heat stress.

中文翻译：

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补充虾青素会影响被动加热过程中细胞HSP的表达。

虾青素是一种功能强大的类胡萝卜素抗氧化剂，广泛存在于海洋生物中，被批准作为食品补充剂。最近的研究表明虾青素在各种健康状态下的有益特性。继补充虾青素的大鼠中潜在的热保护特性的初步报道之后，我们在这里提供了一项新颖的研究结果，研究了虾青素的添加对大鼠中枢温度（Tc）和随之而来的生理应变的热休克反应的影响。在41°C的两个小时的热应激期间，大鼠发展了其温度调节性高温高原，导致虾青素（油脂树脂）治疗组的HSP72和HSP27逐渐增加，而对照组（橄榄油）则没有。