Pain sensation is characterized by abrupt changes in central nervous system activity producing autonomic reactivity. While clinical hypnosis has demonstrated its benefits for children in pain management, it is not clear whether hypnosis modulated autonomic pain response in children in clinical conditions. Here, we studied autonomic responses under hypnosis to sutures in pediatric emergencies. For that, 42 children (mean age: 6.5 years, range 1.5 to 13) were divided into two groups consecutively (hypnosis and control groups), according to their choice. Time-frequency analysis was applied on RR intervals (heart rate interbeat intervals, or RRI) to estimate parasympathetic reactivity based on high frequency power (HF) and the Analgesia Nociception Index (ANI®) and on sympathetic reactivity (low frequency power [LF]) and LF/HF ratio). We observed that RRI and LF/HF ratio varied according to suture and hypnosis (p < 0.05): RRI was higher and LF/HF ratio was lower during sutures in the hypnosis group in comparison to the control group whereas HF and ANI® increased only during hypnosis. To conclude, hypnosis in pediatric emergencies reduces sympathetic cardiac pain reactivity and could be a marker of pain relief under hypnosis, while parasympathetic activity seems to be a better marker of hypnosis.

疼痛感的特征在于中枢神经系统活动的突然变化，从而产生自主反应。尽管临床催眠已显示出对儿童的疼痛管理有益，但尚不清楚催眠是否可调节儿童在临床情况下的自主性疼痛反应。在这里，我们研究了催眠对小儿急症中缝线的自主反应。为此，根据他们的选择，将42名儿童（平均年龄：6.5岁，范围从1.5到13岁）连续分为两组（催眠和对照组）。对RR间隔（心率心跳间隔或RRI）进行了时频分析，以基于高频功率（HF）和止痛痛觉指数（ANI®）和交感反应性（低频功率[LF]）估计副交感反应性）和LF / HF比）。p <0.05）：与对照组相比，催眠组的缝合过程中RRI较高，LF / HF比较低，而HF和ANI®仅在催眠期间增加。总而言之，小儿急症中的催眠会降低交感性心脏疼痛反应性，并且可能是催眠作用下疼痛缓解的标志，而副交感活性似乎是催眠作用的更好标志。