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The Past as Seen by Women and Men With Alzheimer Disease: Sex Differences in Autobiographical Memory.
Alzheimer Disease & Associated Disorders ( IF 2.1 ) Pub Date : 2020-04-01 , DOI: 10.1097/wad.0000000000000363
Mohamad El Haj 1, 2, 3 , Claire Boutoleau-Bretonnière 4 , Karim Gallouj 2
Affiliation  

Background: 

Although there is a large body of research demonstrating the negative effects of Alzheimer disease (AD) on autobiographical memory (ie, memory of personal information), little is known about sex differences in autobiographical retrieval in AD.

Methods: 

We addressed this issue by inviting patients with AD and healthy control participants to retrieve autobiographical memories and analyzed them with regard to specificity, subjective experience (ie, time travel, emotion, and visual imagery), and retrieval time.

Results: 

Analyses demonstrated no significant differences between women and men with AD with regard to autobiographical specificity, time travel, visual imagery, or retrieval time. However, the higher emotional value was attributed to memories by women with AD than by men with AD.

Discussion: 

AD seems to equally affect the ability of women and men with AD to construct specific autobiographical memories, to mentally travel in time to relive these memories, to construct mental visual images during memory retrieval, and to organize and monitor search processes, as the latter are mirrored by retrieval time. However, women with AD seem to attribute greater emotional value to autobiographical memories than men with AD.



中文翻译:

患有阿尔茨海默氏病的女性所见的过去:自传体记忆中的性别差异。

背景: 

尽管有大量研究表明阿尔茨海默氏病(AD)对自传体记忆(即个人信息的记忆)的负面影响,但关于自传体中性别差异的了解甚少。

方法: 

我们通过邀请患有AD的患者和健康对照组的参与者检索自传记忆并针对特异性,主观经验(即时间旅行,情感和视觉图像)和检索时间进行分析,从而解决了这一问题。

结果: 

分析表明,患有AD的男女在自传特异性,时间旅行,视觉图像或检索时间方面无显着差异。然而,患有AD的女性比患有AD的男性具有更高的情感价值。

讨论: 

AD似乎同样会影响患有AD的女性和男性构造特定自传体记忆,及时进行精神旅行以重现这些记忆,在记忆检索过程中构造心理视觉图像以及组织和监视搜索过程的能力,因为后者通过检索时间反映出来。但是,患有AD的女性似乎比具有AD的男性更能赋予自传体记忆以情感价值。

更新日期:2020-04-01
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