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Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
Infectious Agents and Cancer ( IF 3.7 ) Pub Date : 2019-12-01 , DOI: 10.1186/s13027-019-0261-6
Abdulaziz Alamri 1 , B K Adiga 2
Affiliation  

IntroductionAlthough the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital KS is rare, particularly in people without risk factors for HIV infection. Isolated penile KS is an unusual manifestation, especially as solitary nodule with ulceration, in HIV seronegative patient.Case presentationWe report such a case of Kaposi sarcoma showing HHV-8 positivity in an elderly male Arabian patient with a delay in prompt diagnosis, but treated successfully with 3 3 years follow-up after limited local surgical excision.ConclusionThe general practitioners, venereologists and urologists should think of KS as a possibility in such lesion and consider early biopsy.

中文翻译:

包皮环切阴茎中经典卡波西肉瘤的非典型表现,表现为人类疱疹病毒 8 (HHV8) 阳性的溃疡性结节,仅通过局部切除即可成功治疗

引言虽然卡波西肉瘤 (KS) 是艾滋病的定义实体之一,在几乎三分之一的 CD4 细胞计数低的 HIV 感染患者中可见,但在 HIV 血清阴性人群中并不少见,但生殖器 KS 很少见,尤其是在没有风险的人群中艾滋病毒感染的因素。孤立的阴茎 KS 是一种不寻常的表现,尤其是在 HIV 血清学阴性患者中表现为孤立性结节并伴有溃疡。病例介绍我们报告了这样一例卡波西肉瘤病例,该病例在一名阿拉伯老年男性患者中显示 HHV-8 阳性,延迟及时诊断,但成功治疗有限的局部手术切除后随访3-3年。结论全科医生、性病科医生和泌尿科医生应将KS视为此类病变的可能,并考虑早期活检。
更新日期:2019-12-01
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